Medical Electronics
Paragon has developed a broad range of patient-connected electronic instrumentation, such as EMG, ECG, EEG monitors and pulse oximeters. We have also developed novel drug delivery systems, electroporation generators, nerve stimulators, an extracorporeal liver assist device and a bone growth stimulator.

Laser Systems and RF Generators
We have particular expertise developing and producing laser-based instrumentation and radio-frequency (RF) generators. Examples of laser-based instrumentation include a transcranial stroke treatment system, a blood analyzer and a drug dosage measurement system. We have developed RF generators for ablating cardiac tissue, denervating kidney nerves and removing spinal discs, as well as electrosurgery systems for cutting, coagulating and plasma-based treatment.

Minimally-Invasive Devices
Paragon has designed and fabricated minimally-invasive diagnostic and therapeutic devices including spinal surgery devices, an ultrasound-based wrinkle treatment system, orthopedic stent devices, a visualization device for urinary incontinence surgery, a delivery system for treating reflux disease, liposuction equipment, laparoscopic instruments, flexible endoscopic devices and interventional catheter systems.

Laboratory and Biotech Instruments
We have produced instruments such as blood analyzers, immunoassay instruments, automated reagent processing systems, DNA analyzers, stem cell processing instruments, centrifuges and microfluidics processors. Our team has expertise in precision 3-axis motion control, macro/microfluidics, optoelectronics, bar-code scanning, automated pipetting, syringe pumps, precision heating and cooling, peristaltic pumping and pH/pO2/pCO2 control.

Wireless Medical Devices
Paragon has designed and developed implantable sensors and telemetry systems for detecting and datalogging physiological parameters such as temperature and motion. We have also developed wireless, self-propelled capsules that move through the GI tract, as well as radio frequency identification (RFID) systems for tracking expensive drugs and preventing medication errors in hospitals.

Below are a few examples of the products we have developed and manufactured:

Intravascular Cooling System Vapor compression-based hypothermia treatment system using a metallized heat-exchange catheter.	Laser-Based Stroke Treatment System Uses Class IV laser to transmit energy through the skull to the brain with the intent of reducing cell death following ischemic stroke.
Handheld Digital Keratometer Takes digital image of eye and automatically measures diameter of pupil and iris, as well as curvature of cornea.	Extracorporeal Liver Assist Device Large-scale system to automate the incubation of human liver cells in bioreactor cartridges for use in extracorporeal liver assist applications.
Vascular Ablation Device Catheter-based RF ablation system for denervating vessels in certain target organs.	Catheter-Based Atrial Fibrillation Treatment Multi-channel, temperature-controlled RF generator for ablating cardiac tissue in order to treat atrial fibrillation.
Aneurism Coil Deployment System Battery-operated, single-use device to deploy platinum coils into brain aneurisms.	RFID Dispensing Station System for securely dispensing pharmaceuticals and supplies using high-density RFID tags and scanning equipment.
Fingertip Pulse Oximeter Low-cost, high-volume, battery-operated device for displaying heart rate and oxygen saturation level.	Bone Stenting System Early-stage system for reversibly reducing and stabilizing fractures of the long bones using a removable, resorbable stent device.
Hypothermia System Thermoelectric-based cooling system using an intravascular helical balloon catheter.	Therapeutic Ultrasound System High-intensity focused ultrasound (HIFU) system able to visualize and treat tissue for purposes of tightening collagen and reducing the appearance of wrinkles.
Desktop DNA Sequencer Revolutionary tabletop instrument for automated DNA sequencing. (Client and project details confidential.)	Electrosurgery Generator Leading-edge electrosurgery system incorporating traditional cutting and coagulation functions, along with an innovative plasma-based, no-smoke/no-char cutting mode.
Nanofluidics Processor Precision 3-axis motion control system that deposits nanodroplets from 384-well plates onto smart chips, for DNA sequencing purposes.	Intraoperative Spinal Surgery System Evoked-response electromyographic (EMG) system for use with advanced minimally-invasive spinal surgical tools.
EMG-Based Nerve Surveillance System for Spinal Surgery Evoked-response electromyographic (EMG) system for monitoring the proximity of surgical tools to spinal nerve roots.	EMG-Based Pedicle Screw Placement Monitor Evoked-response electromyographic (EMG) system for measuring the integrity of placement of implanted hardware in vertebral pedicles.
15-Minute Immunoassay System for POC Diagnostics Desktop immunoassay system for conducting point-of-care tests such as prostate-specific-antigen (PSA) in less than 15 minutes.	Serum Processor Semi-automated instrument for injecting and heat-sealing a patient serum sample into a reagent processing pouch.
Microfluidic Drug Delivery System Prototype of a wearable infusion pump for drugs such as insulin.	Electroporation Generator Electroporation generator for applying high-voltage and high-current impulses to an electrode array for purposes of accelerating the cellular uptake of vaccine compounds.
Microelectronic Interface to 96-Well Tray for DNA Analysis Clinical laboratory instrument for DNA testing using modified 96-well trays.	12-Station Microfluidic Reagent Processor for DNA Analysis Automated clinical laboratory instrument for DNA testing using microfluidics, microelectronics and careful temperature control.
Centrifuge-Based Autologous Cell Separation System System for processing patient materials in a closed sterile loop using centrifugation and other processes to extract certain cell types for re-infusion into the patient.	Vibratory Platform for Osteoporosis Treatment Device for home-based treatment of osteoporosis based on vibration of the long bones and hip joint at a specific frequency and amplitude.
RF Controller for Catheter-Based Cardiac Ablation System for modulating RF energy over an array of electrodes on a cardiac catheter to selectively ablate tissue for the treatment of atrial fibrillation.	Sling Tension Monitor for Urinary Incontinence Surgery Battery-powered device to allow clinicians to measure the tension of implanted slings used for the treatment of urinary incontinence.
Syringe Adapter for Endoscopic Treatment of GERD Force-amplifying device to allow the injection of a viscous bulking compound through a long endoscopic needle into the lower esophagus for the treatment of GERD.	Patient Medication Tracking System Using RFID System for identifying medications at the patient's bedside using radio frequency identification (RFID) technology.
RFID-Based Controlled Access Refrigerator Controlled-access refrigerator for storing, dispensing and tracking high-value medications using radio frequency identification (RFID) technology.	Bone Growth Stimulator Non-invasive, inductively-coupled bone growth stimulator. Battery powered, microprocessor controlled.
Urethroscope for Incontinence Treatment Fiberoptic instrument for the visualization of the female urethra and for guiding the injection of bulking agents into the urethral wall for the treatment of urinary incontinence.	Muscle Rehabilitation System Battery-operated transcutaneous stimulator for muscle stimulation and rehabilitation.
Pain Control Device Battery-operated transcutaneous electrical nerve stimulator (TENS).